Fourteenth Ischia Summer School - 27 June – 3 July 2015
Geographies of Life

Introduction to the theme

Life’s diversity is today an integral part of the various climates and locales our planet has to offer. Herodotus wrote of the stations of the earth’s life forms, and since Aristotle the sea has also attracted naturalists as a source of wonders that confound land-based classifications. Yet understandings of the spatial distribution of life have changed radically over time. In the ancient world, land and sea formed separate spheres in a structured cosmos of “natural places,” each of which possessed its properly adapted inhabitants. For Aristotle, seals were “monsters,” because they show all the main features of land animals, but live in the wrong place. Living beings could be in the right place or out of place, they could inhabit temperate and marginal (hot or cold) zones, but the patterns were not understood in terms of geographic distribution on a grid of latitude and longitude.

Early modern voyages of exploration added this geographical dimension. Sea and land collapsed into one “terraqueous globe,” and naturalists began to realize that identical climes could harbour very different fauna and flora. At the same time, the concept of species acquired temporal and spatial dimensionality, with species now understood as physical and physiological systems in their own right, rather than forms that matter could take on. Only in the nineteenth century, however, did the spatial distribution of organisms become the subject of a dedicated field of research, biogeography. Alexander von Humboldt’s attempt to derive quantitative biogeographic “laws” led to the realization that the distribution of species did not simply follow the physical environment as it varied with latitude, altitude, and geological conditions, but was the contingent result of migrations, displacements, and hybridisations. Evolutionism, that is, depended not only on the discovery of “deep time” (itself a spatial metaphor), but also on the temporalisation and dynamisation of spatial relations. The consolidation of nation states, as well as colonial and imperial projects, was the political correlate of this development, which was equally visible in the human sciences, with medical topographies feeding into epidemiology, and racial typologies into anthropology and demography.

From the late nineteenth century, when the sea also acquired layers of depth and a detailed topography, an international network of field stations were dedicated, for example, to marine biological and high-altitude research. These institutions facilitated in situ investigations of living organisms and the study of human bodies under extreme conditions. Colonial and imperial surveys, the promotion of agriculture and fisheries by nation states, epidemiology and population genetics, the integration of meteorology and hydrology into climatology, and finally, the use of radioactive isotopes and satellite data in tracking life on a global scale, have turned geographic space into an integral and essential component of contemporary understandings of life on earth. Thus, if the nineteenth century saw the dynamisation of geographic space, the twentieth century saw its experimentalisation, the turning of landscapes into ‘labscapes’, as Robert Kohler called them.

Historians have studied the geographic dimension of the life sciences from a diversity of perspectives, though usually with a focus on particular fields: natural history in the context of exploration and empire, biogeography, oceanography, ecology, epidemiology, demography and medical geography. This summer school adds perspectives from the spatial turn in the history of science, medicine and technology, including studies of transregional and global exchange networks, which have often taken inspiration from imperial studies, oceanic histories, and world history. It also takes account of spatially organized inscription devices, including the lists, catalogues, maps, statistical records, and databases that can synoptically present data gathered from various places.

It was timely to explore the changing relationship between humans and the spatially organized environment also because, confronted by problems of disease control, food security, conservation biology, and climate change, the biosciences themselves increasingly study life as a complex, spatially distributed phenomenon, be it on the micro-scale of biofilms and gut floras, or the macro-scale of the biosphere. This may represent a reawakening after a period when molecular biology dominated, or developments of research programmes that were always alternatives to the molecular paradigm, or the opening up of new spaces for research by the very molecularization of life. At the same time, human geographers had turned their attention to the life sciences as a phenomenon to be addressed with their own tools. Though such concepts as Friedrich Ratzel’s Lebensraum have a long (and problematic) history, geographers had recently begun to study the production of biological knowledge in its own right. Often taking spatial metaphors in the life sciences as a starting point – “boundary,” with its prominent place in immunology, is a telling example – they were exploring the co-production of spatial relations through interactions between humans, both experts and laypeople, and other organisms. The summer school on “Geographies of Life” thus addressed a subject of urgent relevance to the evolving relations of humans with our natural and social environments, and added historical depth to attempts to understand the roles of the life sciences in changing those relations.

For more information

The first International Summer School on Marine ecotoxicology, SSME1, is organized by the Stazione Zoologica Anton Dohrn under the patronage of Ordine Nazionale dei Biologi and will take place in July 2019 from the 1st to the 5th.

SSME1 will provide an advanced training on different classes of traditional and emerging marine pollutants and how biological systems respond to and are affected by these contaminants at all biological levels.

The participants will focus on:

• Marine chemical stressors: metals, antifoulants, nanomaterials, plastics
• Climate changes: global warming, ocean acidification
• Marine natural toxins
• Marine model organisms in ecotoxicology
• Biomarkers and bioindicators in marine environmental monitoring
• Reprotoxicology
• Case studies
• Ecotoxicity tests

The program consists of lectures and practical sessions held by internationally recognized experts and researchers in the field. Practical session will include innovative and standardized toxicity tests for the assessment of ecotoxicological effects in different marine organisms.

This course will allow the participants to acquire methods and approaches for the detection and assessment of the impact of environmental stressors on marine biota.

SSME1 is open to 20 people with basic knowledge in ecotoxicology

The registration fee is 300,00€ (three hundreds/00), which includes documentation, coffee and lunches, but it does not include accommodation.

The Ordine Nazionale dei Biologi (ONB) supports SSME1 with funds to cover the fee for thirteen participants and provides a certificate worth ECM credits (continued medical education) to all participants.

For more information

Protein Evolution: from Environmental Adaptations to Biotechnological Applications

A Summer School on “Protein Evolution” will be held at the Stazione Zoologica Anton Dohrn in Naples on July 24 - 26. The Program will include lectures on theoretical aspects of molecular evolution, sequence data manipulation and alignment, protein structure, molecular modelling, and docking analysis. Lectures will be integrated with practical tutorials; and participants are encouraged to work on their own laptop. The number of participants will be limited to 22, and admission is on a first come, first served basis.

For more information

2016

Arnone, M. I. (2016). Echinoderm systems for gene regulatory studies in evolution and development. Current Opinion in Genetics & Development 39, 129 - 137.

Basu, S., Hadzhiev, Y., Petrosino, G., Nepal, C., Gehrig, J., Armant, O., Ferg, M., Strahle, U., Sanges, R. and Müller, F. (2016). The Tetraodon nigroviridis reference transcriptome: developmental transition, length retention and microsynteny of long non-coding RNAs in a compact vertebrate genome. Scientific Reports 6, 33210.

Berenshtein, I., Rousseau, M., Scata, G., Fiorito, G. and Shashar, N. (2016). Observed and modelled camouflage response of European cuttlefish (Sepia officinalis) to different substrate patch sizes during movement. Frontiers in Physiology 7, 671.

Bevilacqua, S. and Terlizzi, A. (2016). Species surrogacy in environmental impact assessment and monitoring: extending the BestAgg approach to asymmetrical designs. Marine Ecology Progress Series 547, 19-32.

Boni, R., Gallo, A., Montanino, M., Macina, A. and Tosti, E. (2016). Dynamic changes in the sperm quality of Mytilus galloprovincialis under continuous thermal stress. Mol Reprod Dev 83, 162-73.

Brozovic, M., Martin, C., Dantec, C., Dauga, D., Mendez, M., Simion, P., Percher, M., Laporte, B., Scornavacca, C., Di Gregorio, A. et al. (2016). ANISEED 2015: a digital framework for the comparative developmental biology of ascidians. Nucleic Acids Res 44 (D1), D808-D818.

Castellano, I., Migliaccio, O., D'Aniello, S., Merlino, A., Napolitano, A. and Palumbo, A. (2016). Shedding light on ovothiol biosynthesis in marine metazoans. Sci Rep 6, 21506.

Ciezarek, A. G., Dunning, L. T., Jones, C. S., Noble, L. R., Humble, E., Stefanni, S. S. and Savolainen, V. (2016). Substitutions in the Glycogenin-1 Gene Are Associated with the Evolution of Endothermy in Sharks and Tunas. Genome Biol Evol 8, 3011-3021.

Coppola, U., Annona, G., D'Aniello, S. and Ristoratore, F. (2016). Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective. BMC Evol Biol 16, 26.

Costantini, M., Greif, G., Alvarez-Valin, F. and Bernardi, G. (2016). The Anolis Lizard Genome: An Amniote Genome without Isochores? Genome Biol Evol 8, 1048-55.

D'Agostino, Y., Locascio, A., Ristoratore, F., Sordino, P., Spagnuolo, A., Borra, M. and D'Aniello, S. (2016). A Rapid and Cheap Methodology for CRISPR/Cas9 Zebrafish Mutant Screening. Mol Biotechnol 58, 73-8.

De Luca, D., Catanese, G., Procaccini, G. and Fiorito, G. (2016). Octopus vulgaris (Cuvier, 1797) in the Mediterranean Sea: Genetic Diversity and Population Structure. PLoS One 11, e0149496.

Fortunato, A., Boni, R., Leo, R., Nacchia, G., Liguori, F., Casale, S., Bonassisa, P. and Tosti, E. (2016). Vacuoles in sperm head are not associated with head morphology, DNA damage and reproductive success. Reprod Biomed Online 32, 154-161.

Ferramosca, A., Conte, A., Guerra, F., Felline, S., Rimoli, M. G., Mollo, E., Zara, V. and Terlizzi, A. (2016). Metabolites from invasive pests inhibit mitochondrial complex II: A potential strategy for the treatment of human ovarian carcinoma? Biochemical and biophysical research communications 473(4), 1133-1138.

Fortunato, A., Boni, R., Leo, R., Nacchia, G., Liguori, F., Casale, S., Bonassisa, P. and Tosti, E. (2016a). Vacuoles in sperm head are not associated with head morphology, DNA damage and reproductive success. Reproductive BioMedicine Online 32, 154-61.

Fortunato, A. E., Sordino, P. and Andreakis, N. (2016b). Evolution of the SOUL Heme-Binding Protein Superfamily Across Eukarya. J Mol Evol 82, 279-90.

Gallina, A. A., Palumbo, A. and Casotti, R. (2016). Oxidative pathways in response to polyunsaturated aldehydes in the marine diatom Skeletonema marinoi (Bacillariophyceae). J Phycol. 52, 590–598.

Gallo, A., Boni, R., Buttino, I. and Tosti, E. (2016). Spermiotoxicity of nickel nanoparticles in the marine invertebrate Ciona intestinalis (ascidians). Nanotoxicology, 1-9.

Gallo, A. and Tosti, E. (2016). Adverse Effect of Ocean Acidification on Marine Organisms. J Marine Sci Res Dev 6, e139.

Josef, N., Berenshtein, I., Rousseau, M., Scata, G., Fiorito, G. and Shashar, N. (2016). Size Matters: Observed and Modeled Camouflage Response of European Cuttlefish (Sepia officinalis) to Different Substrate Patch Sizes during Movement. Frontiers in Physiology 7.

Karaz, S., Courgeon, M., Lepetit, H., Bruno, E., Pannone, R., Tarallo, A., Thouzé, F., Kerner, P., Vervoort, M., Causeret, F., Pierani, A., D'Onofrio, G. (2016). Neuronal fate specification by the Dbx1 transcription factor is linked to the evolutionary acquisition of a novel functional domain. EvoDevo 7, 1-13.

Mao, C. A., Agca, C., Mocko-Strand, J. A., Wang, J., Ullrich-Luter, E., Pan, P., Wang, S. W., Arnone, M. I., Frishman, L. J. and Klein, W. H. (2016). Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development. Proceedings of the Royal Society B-Biological Sciences 283.

Martella, A., Sepe, R. M., Silvestri, C., Zang, J., Fasano, G., Carnevali, O., De Girolamo, P., Neuhauss, S. C. F., Sordino, P. and Di Marzo, V. (2016). Important role of endocannabinoid signaling in the development of functional vision and locomotion in zebrafish. The FASEB Journal 30, 4275-4288.

Migliaccio, O., Castellano, I., Di Cioccio, D., Tedeschi, G., Negri, A., Cirino, P., Romano, G., Zingone, A. and Palumbo, A. (2016). Subtle reproductive impairment through nitric oxide-mediated mechanisms in sea urchins from an area affected by harmful algal blooms. Scientific Reports 6, 26086.

Moreno-Valcárcel, R., Oliva-Paterna, F. J., Bevilacqua, S., Terlizzi, A. and Fernández-Delgado, C. (2016). Long-term effects of tidal restriction on fish assemblages in east Atlantic coastal marshlands. Marine Ecology Progress Series 543, 209-222.

Pagano, G., Guida, M., Siciliano, A., Oral, R., Kocbas, F., Palumbo, A., Castellano, I., Migliaccio, O., Thomas, P. J. and Trifuoggi, M. (2016). Comparative toxicities of selected rare earth elements: Sea urchin embryogenesis and fertilization damage with redox and cytogenetic effects. Environ Res 147, 453-60.

Perillo, M., Wang, Y. J., Leach, S. D. and Arnone, M. I. (2016). A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus purpuratus larva. BMC Evol Biol 16, 117.

Pugliese, C., Mazza, R., Andrews, P. L., Cerra, M. C., Fiorito, G. and Gattuso, A. (2016). Effect of Different Formulations of Magnesium Chloride Used As Anesthetic Agents on the Performance of the Isolated Heart of Octopus vulgaris. Frontiers in Physiology 7.

Rizzo, F., Coffman, J. A. and Arnone, M. I. (2016). An Elk transcription factor is required for Runx-dependent survival signaling in the sea urchin embryo. Dev Biol. 416, 173–186.

Romano, G., Costantini, M., Sansone, C., Lauritano, C., Ruocco, N. and Ianora, A. (2016). Marine microorganisms as a promising and sustainable source of bioactive molecules. Mar Environ Res. In press; Available online: 3 May 2016.

Ruocco, N., Costantini, M. and Santella, L. (2016). New insights into negative effects of lithium on sea urchin Paracentrotus lividus embryos. Scientific Reports 6.

Ruocco, N., Costantini, S. and Costantini, M. (2016). Blue-Print Autophagy: Potential for Cancer Treatment. Marine Drugs 14, 138.

Ruocco, N., Costantini, S., Guariniello, S. and Costantini, M. (2016). Polysaccharides from the Marine Environment with Pharmacological, Cosmeceutical and Nutraceutical Potential. Molecules 21.

Ruocco, N., Varrella, S., Romano, G., Ianora, A., Bentley, M. G., Somma, D., Leonardi, A., Mellone, S., Zuppa, A. and Costantini, M. (2016). Diatom-derived oxylipins induce cell death in sea urchin embryos activating caspase-8 and caspase 3/7. Aquat Toxicol 176, 128-40.

Shaw, T. J., Osborne, M., Ponte, G., Fiorito, G. and Andrews, P. L. (2016). Mechanisms of wound closure following acute arm injury in Octopus vulgaris. Zoological Lett 2, 8.

Taddei, L., Stella, G. R., Rogato, A., Bailleul, B., Fortunato, A. E., Annunziata, R., Sanges, R., Thaler, M., Lepetit, B., Lavaud, J., Jaubert, M., Finazzi, G., Bouly, J.P., Falciatore, A. (2016). Multisignal control of expression of the LHCX protein family in the marine diatom Phaeodactylum tricornutum. J Exp Bot 67, 3939-51.

Tarallo, A., Angelini, C., Sanges, R., Yagi, M., Agnisola, C. and D'Onofrio, G. (2016). On the genome base composition of teleosts: the effect of environment and lifestyle. BMC Genomics 17, 173.

Tarallo, A., Gambi, M. C. and D'Onofrio, G. (2016b). Lifestyle and DNA base composition in polychaetes. Physiological Genomics 48, 883-888.

Tarallo, A., Yagi, M., Oikawa, S., Agnisola, C. and D'Onofrio, G. (2016). Comparative morpho-physiological analysis between Ciona robusta and Ciona savignyi. Journal of Experimental Marine Biology and Ecology 485, 83-87.

Tosti, E., Boni, R. and Gallo, A. (2016). Ion currents in embryo development. Birth Defects Res C Embryo Today 108, 6-18.

Tosti, E. and Menezo, Y. (2016). Gamete activation: basic knowledge and clinical applications. Hum Reprod Update 22, 420-39.

Valero-Gracia, A., Marino, R., Crocetta, F., Nittoli, V., Tiozzo, S. and Sordino, P. (2016a). Comparative localization of serotonin-like immunoreactive cells in Thaliacea informs tunicate phylogeny. Frontiers in Zoology 13.

Valero-Gracia, A., Petrone, L., Oliveri, P., Nilsson, D. E. and Arnone, M. I. (2016b). Non-directional photoreceptors in the pluteus of Strongylocentrotus purpuratus. Frontiers in Ecology and Evolution 4.

Varrella, S., Romano, G., Costantini, S., Ruocco, N., Ianora, A., Bentley, M. G. and Costantini, M. (2016). Toxic Diatom Aldehydes Affect Defence Gene Networks in Sea Urchins. PLoS One 11, e0149734.

Varrella, S., Romano, G., Ruocco, N., Ianora, A., Bentley, M. G. and Costantini, M. (2016). First Morphological and Molecular Evidence of the Negative Impact of Diatom-Derived Hydroxyacids on the Sea Urchin Paracentrotus lividus. Toxicol Sci 151, 419-33.

Verde, C., Giordano, D., Bellas, C. M., di Prisco, G. and Anesio, A. M. (2016). Chapter Four-Polar Marine Microorganisms and Climate Change. Advances in Microbial Physiology 69, 187-215.

Books and/or Book Chapters

Lowe, E. K., Cuomo, C. and Arnone, M. I. (2016). A Differential Transcriptomic Approach to Compare Target Genes of Homologous Transcription Factors in Echinoderm Species. In Dynamics of Mathematical Models in Biology: Springer International Publishing.

Martinez-Morales, J. R. and Locascio, A. (2016). Vertebrate Eye Evolution. In Organogenetic Gene Networks, (ed. J. Castelli-Gair Hombría, Bovolenta, Paola (Eds)), pp. 275-298: Springer International Publishing.

2015

ISI Journal Papers

Affinito, O., Andreakis, N., Caputi, L., Marino, R., Pannone, R., Sordino, P. and Procaccini, G. (2015). High connectivity and directional gene flow in European Atlantic and Mediterranean populations of Ciona intestinalis sp. A. Marine Ecology 36, 1230-1243.

Andrikou, C. and Arnone, M. I. (2015). Too many ways to make a muscle: Evolution of GRNs governing myogenesis. Zoologischer Anzeiger 256, 2-13.

Andrikou, C., Pai, C. Y., Su, Y. H. and Arnone, M. I. (2015). Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm. Elife 4.

Annona, G., Holland, N. D. and D'Aniello, S. (2015). Evolution of the notochord. Evodevo 6, 30.

Arnone, M. I. and Hejnol, A. (2015). Genomics going wild: Marine sampling for studies of evolution and development. Marine Genomics 24, 119-120.

Caputi, L., Crocetta, F., Toscano, F., Sordino, P. and Cirino, P. (2015). Long-term demographic and reproductive trends in Ciona intestinalis sp A. Marine Ecology-an Evolutionary Perspective 36, 118-128.

Castellano, I., Ercolesi, E., Romano, G., Ianora, A. and Palumbo, A. (2015a). The diatom-derived aldehyde decadienal affects ERK signaling during metamorphosis of the ascidian Ciona intestinalis. Open biology 5, 140-182.

Castellano, I., Ercolesi, E., Romano, G., Ianora, A. and Palumbo, A. (2015b). The diatom-derived aldehyde decadienal affects life cycle transition in the ascidian Ciona intestinalis through nitric oxide/ERK signalling. Open Biology 5.

Costantini, M. (2015). An overview on genome organization of marine organisms. Mar Genomics 24 Pt 1, 3-9.

Costantini, S., Romano, G., Rusolo, F., Capone, F., Guerriero, E., Colonna, G., Ianora, A., Ciliberto, G. and Costantini, M. (2015). Anti-Inflammatory Effects of a Methanol Extract from the Marine Sponge Geodia cydonium on the Human Breast Cancer MCF-7 Cell Line. Mediators Inflamm 2015, 204975.

Crocetta, F., Marino, R., Cirino, P., Macina, A., Staiano, L., Esposito, R., Pezzotti, M. R., Racioppi, C., Toscano, F., De Felice, E., Locascio, A., Ristoratore, F., Spagnuolo, A., Zanetti, L., Branno, M. and Sordino, P. (2015). Mutation studies in ascidians: a review. Genesis 53, 160-9.

D'Alessandro, A., Pesce, M., Arnone, M. I., Zito, F. P., Andreozzi, P., Efficie, E., Civiletti, R., Affinito, G., Cuomo, R. and Sarnelli, G. (2015). Impact of upper gastrointestinal symptoms perception on BMI in GERD patients. Neurogastroenterology and Motility 27, 13-14.

D'Aniello, S., Delroisse, J., Valero-Gracia, A., Lowe, E. K., Byrne, M., Cannon, J. T., Halanych, K. M., Elphick, M. R., Mallefet, J., Kaul-Strehlowi, S., Lowe, C.J., Flammang, P., Ullrich-Luter, E., Wanninger, A., Arnone, M.I. (2015). Opsin evolution in the Ambulacraria. Marine Genomics 24, 177-183.

Danovaro, R., Costantini, M. and Verde, C. (2015). The marine genome: structure, regulation and evolution. Mar Genomics 24 Pt 1, 1-2.

De Luca, D., Catanese, G., Fiorito, G. and Procaccini, G. (2015). A new set of pure microsatellite loci in the common octopus Octopus vulgaris Cuvier, 1797 for multiplex PCR assay and their cross-amplification in O. maya Voss & Solis Ramirez, 1966. Conservation Genetics Resources 7, 299-301.

Di Cristina, G., Andrews, P., Ponte, G., Galligioni, V. and Fiorito, G. (2015). The impact of Directive 2010/63/EU on cephalopod research. Invertebrate Neuroscience 15, 1-7.

Di Dato, V., Musacchia, F., Petrosino, G., Patil, S., Montresor, M., Sanges, R. and Ferrante, M. I. (2015). Transcriptome sequencing of three Pseudo-nitzschia species reveals comparable gene sets and the presence of Nitric Oxide Synthase genes in diatoms. Sci Rep 5, 12329.

Elphick, M. R., Semmens, D. C., Blowes, L. M., Levine, J., Lowe, C. J., Arnone, M. I. and Clark, M. S. (2015). Reconstructing SALMFamide Neuropeptide Precursor Evolution in the Phylum Echinodermata: Ophiuroid and Crinoid Sequence Data Provide New Insights. Front Endocrinol (Lausanne) 6, 2.

Esposito, R., Racioppi, C., Pezzotti, M. R., Branno, M., Locascio, A., Ristoratore, F. and Spagnuolo, A. (2015). The ascidian pigmented sensory organs: structures and developmental programs. Genesis 53, 15-33.

Fiorito, G., Affuso, A., Basil, J., Cole, A., de Girolamo, P., D'Angelo, L., Dickel, L., Gestal, C., Grasso, F., Kuba, M. Mark, F., Melillo, D., Osorio, D., Perkins, K., Ponte, G., Shashar, N., Smith, D., Smith, J., Andrews, P.L. (2015). Guidelines for the Care and Welfare of Cephalopods in Research -A consensus based on an initiative by CephRes, FELASA and the Boyd Group. Lab Anim 49, 1-90.

Fortunato, A. and Tosti, E. (2015). Sperm Vacuoles and Reproductive Outcome. Journal of Fertilization: In Vitro-IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology 2015.

Fortunato, A. E., Sordino, P. and Andreakis, N. (2016). Evolution of the SOUL Heme-Binding Protein Superfamily Across Eukarya. J Mol Evol 82, 279-90.

Gallo, A. and Tosti, E. (2015). Antifouling Compounds Endangering Marine Invertebrates Reproduction. J Environ Monit 13, 2360-2388.

Gallo, A. and Tosti, E. (2015). Ion currents involved in gamete physiology. Int J Dev Biol 59, 261-70.

Gallo, A. and Tosti, E. (2015). Reprotoxicity of the antifoulant chlorothalonil in ascidians: an ecological risk assessment. PLoS One 10, e0123074.

Gallo, A. and Tosti, E. (2015). The Ascidian Ciona Intestinalis as Model Organism for Ecotoxicological Bioassays. Journal of Marine Science. Research & Development 5, 1.

Guerriero, E., Capone, F., Accardo, M., Sorice, A., Costantini, M., Colonna, G., Castello, G. and Costantini, S. (2015). GPX4 and GPX7 over-expression in human hepatocellular carcinoma tissues. Eur J Histochem 59, 2540.

Holden-Dye, L., Fiorito, G. and Ponte, G. (2015). Invertebrate neuroscience and CephsInAction at the Mediterranean Society for Neuroscience Meeting Cagliari 2015. Invert Neurosci 15, 6.

Josef, N., Berenshtein, I., Fiorito, G., Sykes, A. V. and Shashar, N. (2015). Camouflage during movement in the European cuttlefish (Sepia officinalis). J Exp Biol 218, 3391-8.

Kumar, A., Castellano, I., Patti, F. P., Palumbo, A. and Buia, M. C. (2015). Nitric oxide in marine photosynthetic organisms. Nitric Oxide 47, 34-9.

Lettieri, A., Esposito, R., Ianora, A. and Spagnuolo, A. (2015). Ciona intestinalis as a marine model system to study some key developmental genes targeted by the diatom-derived aldehyde decadienal. Mar Drugs 13, 1451-65.

Limatola, N., Chun, J. T., Kyozuka, K. and Santella, L. (2015). Novel Ca²⁺ increases in the maturing oocytes of starfish during the germinal vesicle breakdown. Cell Calcium 58, 500-10.

Mariotti, M., Santesmasses, D., Capella-Gutierrez, S., Mateo, A., Arnan, C., Johnson, R., D'Aniello, S., Yim, S. H., Gladyshev, V. N., Serras, F., Corominas, M., Gabaldón, T., Guigó, R. (2015). Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization. Genome Res 25, 1256-67.

Migliaccio, O., Castellano, I., Cirino, P., Romano, G. and Palumbo, A. (2015). Maternal Exposure to Cadmium and Manganese Impairs Reproduction and Progeny Fitness in the Sea Urchin Paracentrotus lividus. PLoS One 10, e0131815.

Musacchia, F., Basu, S., Petrosino, G., Salvemini, M. and Sanges, R. (2015). Annocript: a flexible pipeline for the annotation of transcriptomes able to identify putative long noncoding RNAs. Bioinformatics 31, 2199-201.

Pappalardo, A., Porreca, I., Caputi, L., De Felice, E., Schulte-Merker, S., Zannini, M. and Sordino, P. (2015). Thyroid development in zebrafish lacking Taz. Mech Dev 138 Pt 3, 268-78.

Patil, S., Moeys, S., von Dassow, P., Huysman, M. J., Mapleson, D., De Veylder, L., Sanges, R., Vyverman, W., Montresor, M. and Ferrante, M. I. (2015). Identification of the meiotic toolkit in diatoms and exploration of meiosis-specific SPO11 and RAD51 homologs in the sexual species Pseudo-nitzschia multistriata and Seminavis robusta. BMC Genomics 16, 930.

Russo, M. T., Annunziata, R., Sanges, R., Ferrante, M. I. and Falciatore, A. (2015). The upstream regulatory sequence of the light harvesting complex Lhcf2 gene of the marine diatom Phaeodactylum tricornutum enhances transcription in an orientation- and distance-independent fashion. Mar Genomics 24 Pt 1, 69-79.

Santella, L. and Dale, B. (2015). Assisted yes, but where do we draw the line? Reprod Biomed Online 31, 476-8.

Santella, L., Limatola, N. and Chun, J. T. (2015). Calcium and actin in the saga of awakening oocytes. Biochem Biophys Res Commun 460, 104-13.

Stefanni, S., Castilho, R., Sala-Bozano, M., Robalo, J. I., Francisco, S. M., Santos, R. S., Marques, N., Brito, A., Almada, V. C. and Mariani, S. (2015). Establishment of a coastal fish in the Azores: recent colonisation or sudden expansion of an ancient relict population? Heredity 115, 527-37.

Vassalli, Q. A., Anishchenko, E., Caputi, L., Sordino, P., D'Aniello, S. and Locascio, A. (2015). Regulatory elements retained during chordate evolution: coming across tunicates. Genesis 53, 66-81.

Vitale, L., Patil, S., Basu, S., Sanges, R., Ferrante, M. and Montresor, M. (2015). Mating Type related genes in Pseudo-nitzschia multistriata. European Journal of Phycology 50, 117-118.

Yazaki, I., Tsurugaya, T., Santella, L., Chun, J. T., Amore, G., Kusunoki, S., Asada, A., Togo, T. and Akasaka, K. (2015). Ca²⁺ influx-linked protein kinase C activity regulates the beta-catenin localization, micromere induction signalling and the oral-aboral axis formation in early sea urchin embryos. Zygote 23, 426-46.

Zarrella, I., Ponte, G., Baldascino, E. and Fiorito, G. (2015). Learning and memory in Octopus vulgaris: a case of biological plasticity. Curr Opin Neurobiol 35, 74-9.

Zucchelli, S., Cotella, D., Takahashi, H., Carrieri, C., Cimatti, L., Fasolo, F., Jones, M. H., Sblattero, D., Sanges, R., Santoro, C., Persichetti, F., Carninci, P., Gustincich, S. (2015). SINEUPs: A new class of natural and synthetic antisense long non-coding RNAs that activate translation. RNA Biol 12, 771-9.

Books and/or Book Chapters

Anishchenko, E. and D’Aniello, S. (2015). Tunicate Neurogenesis: The Case of the SoxB2 Missing CNE. In Mathematical Models in Biology: Bringing Mathematics to Life, eds. V. Zazzu B. M. Ferraro and R. M. Guarracino, pp. 99-108. Cham: Springer International Publishing.

Arnone, M. I., Byrne, M. and Martinez, P. (2015). Echinodermata. In Evolutionary Developmental Biology of Invertebrates 6: Deuterostomia, (ed. A. Wanninger), pp. 1-58. Vienna 978-3-7091-1856-6: Springer Vienna.

Gallo, A. and Tosti, E. (2015). Cytoskeletal Elements and the Reproductive Success in Animals. In The Cytoskeleton in Health and Disease, (ed. H. Schatten), pp. 147-166. New York, NY 978-1-4939-2904-7: Springer New York.

Ponte, G. and Fiorito, G. (2015). Immunohistochemical Analysis of Neuronal Networks in the Nervous System of Octopus vulgaris. In Immunocytochemistry and Related Techniques, eds. A. Merighi and L. Lossi), pp. 63-79. New York, NY: Springer New York.

Abstracts

Amato, A., Kooistra, W., Peters, F., Ribera d’Alcalà, M., Sanges, R., Iudicone, D. and Ferrante, M. I. (2015). Isotropic marine microturbulence affects diatom chain composition. In 2015 Aquatic Sciences Meeting,  (ed. A. f. t. S. o. L. a. Oceanography). Granada, Spain.

Castellano, I., Ercolesi, E., Romano, G., Ianora, A. and Palumbo, A. (2015). The diatom-derived aldehyde decadienal affects ERK signaling during metamorphosis of the ascidian Ciona intestinalis, vol. 281, pp. 339-339: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA.

Kumar, A., Patti, F. P., Castellano, I., Delledonne, M., Palumbo, A. and Buia, M. C. (2015). Sargassum vulgare adaptation in acidified waters at natural CO2 vents (Ischia Island, Italy), vol. 50, pp. 195-195: TAYLOR & FRANCIS LTD 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND.

Ruocco, M., Gabriele, P., Musacchia, F., Sanges, R., Olivé, I., Costa, M. M., Barrote, I., Santos, R. and Silva, J. (2015). Cymodocea nodosa response to simulated CO2-driven ocean acidification: a first insight from global transcriptome profiling: PeerJ PrePrints.

2014

ISI Journal Papers

Affinito O., Andreakis N., Caputi L., Marino R., Pannone R., Sordino P., Procaccini G. (2014). High connectivity and directional gene flow in European Atlantic and Mediterranean populations of Ciona intestinalis sp. A. Marine ecology, First published online: http://onlinelibrary.wiley.com/doi/10.1111/maec.12226/abstract 

Amodio P., Andrews P., Salemme M., Ponte G., Fiorito G. (2014). The Use of Artificial Crabs for Testing Predatory Behavior and Health in the Octopus. ALTEX, 31(4): 494-499.

Annunziata R. and Arnone M.I. (2014). A dynamic network of regulatory interactions explains ParaHox gene control of gut patterning in the sea urchin embryo. Development, 141: 2462-72.

Arienzo M., Toscano F., Di Fraia M., Caputi L., Sordino P., Guida M., Aliberti F., Ferrara L. (2014). An assessment of contamination of the Fusaro Lagoon (Campania Province, southern Italy) by trace metals. Environmental Monitoring Assessment, 186(9): 5731-5747. DOI: 10.1007/s10661-014-3816-4.

Bezzaouia A., Gallo A., Silvestre F.,  Tekaya S., Tosti E. (2014). Distribution pattern and activity of  mitochondria during oocyte growth and maturation in the ascidian Styela plicata. Zygote, 22(4): 462-469. DOI: 10.1017/S0967199412000640.

Castellano I., Ercolesi E., Palumbo A. (2014). Nitric oxide affects ERK signaling through down-regulation of MAP kinase phosphatase levels during larval development of the ascidian Ciona intestinalis. PLoS One, 9(7): e102907. DOI:10.1371/journal.pone.0102907.

Chun J.T., Limatola N., Vasilev F., Santella L. (2014). Early events of fertilization in sea urchin eggs are sensitive to actin-binding organic molecules. Biochemical and biophysical research communications, 450(3): 1166-1174. DOI: 10.1016/j.bbrc.2014.06.057.

Cima F., Caicci F., Sordino P. (2014). The haemocytes of the salp Thalia democratica (Tunicata, Thaliacea): an ultrastructural and histochemical study in the oozoid. Acta Zoologica, 95(4): 375-391. 

Conte I., Merella S., Garcia-Manteiga J.M., Migliore C., Lazarevic D., Carrella S., Marco-Ferreres R., Avellino R., Davidson N.P., Emmett W., Sanges R., Bockett N., Van Heel D., Meroni G., Bovolenta P., Stupka E., Banfi S. (2014). The combination of transcriptomics and informatics identifies pathways targeted by miR-204 during neurogenesis and axon guidance. Nucleic Acids Res, 42(12): 7793-806. DOI: 10.1093/nar/gku498.

Dattolo E., Ruocco M., Brunet C., Lorenti M., Lauritano C., D'Esposito D., De Luca P., Sanges R., Mazzuca S., Procaccini G. (2014). Response of the seagrass Posidonia oceanica to different light environments: Insights from a combined molecular and photo-physiological study. Marine Environmental Research, 101: 225-236. DOI: 10.1016/j.marenvres.2014.07.010.

De Felice B., Annunziata A., Fiorentino G., Manfellotto F., D’Alessandro R., Marino R., Borra M., Biffali E. (2014). Telomerase expression in amyotrophic lateral sclerosis (ASL) patients. Journal of Human Genetics, 59(10): 555-561.

De Felice E., Porreca I., Alleva E., De Girolamo P., Ciriaco E., Germanà A., Sordino P. (2014). Localization of BDNF expression in the developing brain of zebrafish. Journal of Anatomy, 224(5): 564-574. DOI: 10.1111/joa.12168.

Delroisse J., Ullrich-Lüter E., Ortega-Martinez O., Dupont S., Arnone M.I., Mallefet J., Flammang P. (2014). High opsin diversity in a non-visual infaunal brittle star. BMC Genomics, 15: 1035. 

Dishaw L.J., Flores-Torres J., Lax S., Gemayel C., Leigh B., Melillo D., Mueller M.G., Natale L., Zucchetti I., De Santis R., Pinto M.R., Litman G.W., Gilbert J.A. (2014). The gut of geographically disparate Ciona intestinalis harbors a core microbiota. PLoS One, 9(4): e93386. DOI:10.1371/journal.pone.0093386.

Dvořák P., Casamatta D.A., Poulíčková A., Hašler P., Ondřej V., Sanges R. (2014). Synechococcus: 3 billion years of global dominance. Molecular Ecology, 23(22): 5538-5551. DOI: 10.1111/mec.12948. 

Fiorito G., Affuso A., Anderson D., Basil J., Bonnaud L., Botta G., Cole A., D'Angelo L., Girolamo P., Dennison N., Dickel L., Cosmo A., Cristo C., Gestal C., Fonseca R., Grasso F., Kristiansen T., Kuba M., Maffucci F., Manciocco A., Mark F., Melillo D., Osorio D., Palumbo A., Perkins K., Ponte G., Raspa M., Shashar N., Smith J., Smith D., Sykes A., Villanueva R., Tublitz N., Zullo L., Andrews P. (2014). Cephalopods in neuroscience: regulations, research and the 3Rs. Invertebrate Neuroscience 14(1): 13-36.

Gallina A.A., Brunet C., Palumbo A., Casotti R. (2014). The Effect of Polyunsaturated Aldehydes on Skeletonema marinoi (Bacillariophyceae): The Involvement of Reactive Oxygen Species and Nitric Oxide. Marine Drugs, 12: 4165-4187. DOI:10.3390/md12074165.

Guariniello S., Colonna G., Raucci R., Costantini M., Di Bernardo G., Bergantino F., Castello G., Costantini S. (2014). Structure-function relationship and evolutionary history of the human selenoprotein M (SelM) found over-expressed in hepatocellular carcinoma. BBA-Proteins and Proteomics, 1844: 447-456. 

Josef N., Mann O., Sykes A.V., Fiorito G., Reis J., Maccusker S., Shashar N. (2014). Depth perception: cuttlefish (Sepia officinalis) respond to visual texture density gradients. Animal Cognition, 17(6): 1393-1400.

Liberti A., Melillo D., Zucchetti I., Natale L., Dishaw L.J., Litman G.W., De Santis R., Pinto M.R. (2014). Expression of Ciona intestinalis variable region-containing chitin-binding proteins during development of the gastrointestinal tract and their role in host-microbe interactions. PLoS One, 9(5): e94984. DOI:10.1371/journal.pone.0094984.

Migliaccio O., Castellano I., Romano G., Palumbo A. (2014). Stress response to cadmium and manganese in Paracentrotus lividus developing embryos is mediated by nitric oxide. Aquatic Toxicology, 156:125-134.

Perillo M. and Arnone M.I. (2014). Characterization of insulin-like peptides (ILPs) in the sea urchin Strongylocentrotus purpuratus: insights on the evolution of the insulin family. General and Comparative Endocrinology, 205: 68-79. 

Pezzotti M.R., Locascio A., Racioppi C., Fucci L., Branno M. (2014). Auto and cross regulatory elements control Onecut expression in the ascidian nervous system. Developmental Biology, 390, 273-287.

Porreca I., D’Angelo F., Gentilcore D., Carchia E., Amoresano A., Affuso A,. Ceccarelli M., De Luca P., Esposito L., Guadagno F.M., Mallardo M., Nardone A., Maccarone S., Pane F., Scarfò M., Sordino P., De Felice M., Ambrosino C. (2014). Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution. BMC Genomics, 15: 1067. DOI: 10.1186/1471-2164-15-1067.

Racioppi C., Kamal A. K., Razy-Krajka F., Gambardella G., Zanetti L., di Bernardo D., Sanges R., Christiaen A. L., Ristoratore F. (2014). Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis. Nature Communications, 5: 4830. DOI: 10.1038/ncomms5830.

Roberts J.A., Miguel-Escalada I., Slovik K.J., Walsh K.T., Hadzhiev Y., Sanges R., Stupka E., Marsh E.K., Balciuniene J., Balciunas D., Müller F. (2014). Targeted transgene integration overcomes variability of position effects in zebrafish. Development, 141(3): 715-724. DOI: 10.1242/dev.100347. 

Russo G.L., Russo M., Castellano I,. Napolitano A., Palumbo A. (2014). Ovothiol isolated from sea urchin oocytes induces autophagy in Hep-G2 cell line. Marine Drugs, 12: 4069-4085. DOI: 10.3390/md12074069.

Russo M.T., Racioppi C., Zanetti L., Ristoratore F. (2014). Expression of a single prominin homolog in the embryo of the model chordate Ciona intestinalis. Gene Expression Patterns, 15(1): 38-45. DOI: 10.1016/j.gep.2014.04.001.

Salvemini M., Arunkumar K.P., Nagaraju J., Sanges R., Petrella V., Tomar A., Zhang H., Zheng W., Saccone G. (2014). De novo assembly and transcriptome analysis of the Mediterranean fruit fly Ceratitis capitata early embryos. PLoS One, 9(12): e114191. DOI: 10.1371/journal.pone.0114191. 

Sansone C., Braca A., Ercolesi E., Romano G., Palumbo A., Casotti R., Francone M., Ianora A. (2014). Diatom-derived polyunsaturated aldehydes activate cell death in human cancer cell lines but not normal cells. PLoS One, 9: e101220. DOI: 10.1371/journal.pone.0101220.

Sorrenti G., Bagnoli A., Miraglia V., Crocetta F., Vitiello V., Ristoratore F., Cirino P., Sansone G., Sordino P. (2014). Investigating sperm cryopreservation in a model tunicate, Ciona intestinalis sp. A. Cryobiology. 68.(1): 43-49 DOI: 10.1016/j.cryobiol.2013.11.005.

Stolfi A., Lowe K.E., Racioppi C., Ristoratore F., Brown C.T., Swalla J.B., Christiaen L. (2014). Divergent mechanisms regulate conserved cardiopharyngeal development and gene expression in distantly related ascidians. eLife, 3: e03728. DOI: 10.7554.

Varrella S., Romano G., Ianora A., Bentley M.G., Ruocco N., Costantini M. (2014). Molecular response to toxic diatom-derived aldehydes in the sea urchin Paracentrotus lividus. Marine Drugs, 12: 2089-2113.

Other Publications

De Luca D., Catanese G., Procaccini G., Fiorito G. (2014). An integration of historical records and genetic data to the assessment of global distribution and population structure in Octopus vulgaris. Frontiers in Ecology and Evolution, 2: DOI=10.3389/fevo.2014.00055.

Zuppa A., Costantini S., Costantini M. (2014). Comparative sequence analysis of bacterial symbionts from the marine sponges Geodia cydonium and Ircinia muscarum. Bioinformation, 10(4):196-200.

Chapters

Migliaccio O., Castellano I., Romano G., Palumbo A.  (2014). Response of sea urchin to environmental stress. In: Banks E.R. (Ed.). Sea Urchins: Habitat, Embryonic Development and Importance in the Environment. New York. Nova Science Publishers: 29‐51.

Santella L., Limatola N., Chun J.T. (2014). Actin Cytoskeleton and Fertilization in Starfish Eggs. In: Sawada H., Inoue N., Iwano M. (Eds.). Sexual Reproduction in Animals and Plants. Tokyo, Japan. Springer: 141-155. 

Tricarico E., Amodio P., Ponte G., Fiorito G. (2014). Cognition and Recognition in the Cephalopod Mollusc Octopus vulgaris: Coordinating Interaction with Environment and Conspecifics. In: Witzany, G. (Ed.). Biocommunication of Animals. Netherlands. Springer: 337-349.

2013

ISI Journal Papers

Andrikou C., Iovene E., Rizzo F., Oliveri P., Arnone M.I. (2013). Myogenesis in the sea urchin embryo: the molecular fingerprint of the myoblast precursors. EvoDevo, 4(1):33. DOI: 10.1186/2041-9139-4-33.

Annunziata R., Martinez P., Arnone M.I. (2013). Intact cluster and chordate-like expression of ParaHox genes in a sea star. BMC Biology, 11: 68. DOI: 10.1186/1741-7007-11-68.

Annunziata R., Perillo M., Andrikou C,. Cole A., Martinez P., Arnone M.I. (2013). Pattern and Process During Sea Urchin Gut Morphogenesis: the Regulatory Landscape. Genesis, 52(3): 251-268. DOI: 10.1002/dvg.22738.

Basu S., Müller F., Sanges R. (2013). Examples of sequence conservation analyses capture a subset of mouse long non-coding RNAs sharing homology with fish conserved genomic elements. BMC Bioinformatics, 14(Suppl 7): S14. DOI: 10.1186/1471-2105-14-S7-S14.

Chun J.T., Vasilev F., Santella L. (2013). Antibody Against The Actin-Binding Protein Depactin Attenuates Ca²⁺ Signaling In Starfish Eggs. Biochemical and Biophysical Research Communications, 441(2): 301-307.

Costantini M., Alvarez-Valin F., Costantini S., Cammarano R., Bernardi G. (2013). Compositional patterns in the genomes of unicellular eukaryotes. BMC Genomics, 14: 755. DOI: 10.1186/1471-2164-14-755.

Costantini S., Sharma A., Raucci R., Costantini M., Autiero I., Colonna G. (2013). Genealogy of an ancient protein family: the Sirtuins, a family of disordered members. BMC Evolutionary Biology, 13: 60. DOI: 10.1186/1471-2148-13-60.

Ferriero R., Manco G., Lamantea E., Nusco E., Ferrante M.I., Sordino P., Stacpoole P.W., Lee B., Zeviani M., Brunetti-Pierri N. (2013). Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis. Science Translational Medicine, 5: 175ra31. DOI: 10.1126/scitranslmed.3004986.

Gallo A., Russo G.L., Tosti E. (2013). T-type Ca²⁺ current activity during oocyte growth and maturation in the ascidian Styela plicata. PLoS One, 8(1): 54e604. DOI: 10.1371/journal.pone.0054604.

Gallo A., Tosti E. (2013). Adverse Effect of Antifouling Compounds on the Reproductive Mechanisms of the Ascidian Ciona intestinalis. Marine Drugs, 11: 3554-3568. DOI: 10.3390/md11093554.

Ikuta T., Chen Y.C., Annunziata R., Ting H.C., Tung C.H., Koyanagi R., Tagawa K., Humphreys T., Fujiyama A., Saiga H., Satoh N., Yu J.K., Arnone M.I., Su Y.H. (2013). Identification of an intact ParaHox cluster with temporal colinearity but residual spatial colinearity in the hemichordate Ptychodera flava. BMC Evolutionary Biology, 13(1): 129.

Locatello L., Fiorito G., Finos L., Rasotto M. B. (2013). Behavioural and immunological responses to an immune challenge in Octopus vulgaris. Physiology & Behavior, 122: 93-99. DOI: 10.1016/j.physbeh.2013.08.029.

Mattiello T., d’Ischia M., Palumbo A. (2013). Nitric oxide in chromatic body patterning elements of Sepia officinalis. Journal of Experimental Marine Biology and Ecology, 447: 128-131. DOI:10.1016/j.jembe.2013.02.019.

Pascual-Anaya J., D’Aniello S., Kuratani S., Garcia-Fernàndez J. (2013). Evolution of the Hox clusters in deuterostomes. BMC Developmental Biology, 13: 26. DOI:10.1186/1471-213X-13-26.

Peterson K.J., Su Y.H., Arnone M.I., Swalla B., King B. (2013). MicroRNAs Support the Monophyly of Enteropneust Hemichordates. Journal of experimental zoology. Part B, Molecular and developmental evolution, 320(6): 368-74. DOI: 10.1002/jez.b.22510.

Sanges R., Hadzhiev Y., Gueroult-Bellone M., Roure A., Ferg M., Meola N., Amore G., Basu S., Brown E.R., De Simone M., Petrera F., Licastro D., Strähle U., Banfi S., Lemaire P., Birney E., Müller F., Stupka E. (2013). Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development. Nucleic Acids Research, 41(6): 3600-3618. DOI: 10.1093/nar/gkt030.

Tosti E., Boni R., Gallo A., Silvestre F. (2013). Ion currents modulating oocyte maturation in animals. Systems Biology in Reproductive Medicine, 59(2): 61-68. DOI: 10.3109/19396368.2012.758790.

Ullrich-Lüter E., D’Aniello S., Arnone M.I. (2013). C-opsin expressing photoreceptors in echinoderms. Integrative & Comparative Biology, 53: 27-38. DOI: 10.1093/icb/ict050.

Chapters

Amodio P. and Fiorito G. (2013). Observational and Other Types of Learning in Octopus' in Menzel R. and Benjamin P.R. (Eds.). Invertebrate Learning and Memory. London, UK. Elsevier: 293-302.

Chun J.T. and Santella L. (2013). Intracellular Calcium Waves' in Lennarz W.J. and Lane M.D. (Eds.) The Encyclopedia of Biological Chemistry. Waltham, USA. Academic Press: 648-647.

Santella L., and Chun J.T. (2013). Calcium signaling by cyclic ADP-ribose and NAADP' in Lennarz W.J. and Lane M.D. (Eds.) The Encyclopedia of Biological Chemistry. Waltham, USA. Academic Press: 331-336.

2012

ISI Journal Papers

Balato A., Lembo S., Mattii M., Schiattarella M., Marino R., De Paulis A., Balato A. (2012). IL-33 is secreted by psoriatic keratinocytes and induces pro-inflamation cytokines via keratinocyte and mast cell activation. Experimental dermatology, 21(11): 892-4. Erratum in: Experimental dermatology: 21(12):977. DOI: 10.1111/exd.12027.

Costantini M., Auletta F., Bernardi G. (2012). The distribution of "new" and "old" Alu sequences in the human genome: the solution of a "mystery". Molecular Biology and Evolution, 29(1): 421-427. DOI: 10.1093/molbev/msr242.

Ercolesi E., Tedeschi G., Fiore G., Negri A., Maffioli E., d’Ischia M., Palumbo A. (2012). Protein nitration as footprint of oxidative stress-related nitric oxide signaling pathways in developing Ciona intestinalis. Nitric Oxide, 27(1): 18-24. DOI: 10.1016/j.niox.2012.03.012.

Esposito R., D’Aniello S., Squarzoni P., Pezzotti M.R., Ristoratore F., Spagnuolo A. (2012). New Insights into the Evolution of Metazoan Tyrosinase Gene Family. PLoS ONE, 7: e35731. DOI: 10.1371/journal.pone.0035731.

Fago A., Jensen F.B., Tota B., Feelisch M., Olson K.R., Helbo S., Lefevre S., Mancardi D., Palumbo A., Sandvik G.K., Skovgaard N. (2012). Integrating nitric oxide, nitrite and hydrogen sulfide signaling in the physiological adaptations to hypoxia: a comparative approach. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 162(1): 1-6. DOI: 10.1016/j.cbpa.2012.01.011.

Gallo A., Costantini M. (2012). Glycobiology in reproductive processes in marine animals: the state of art. Marine Drugs, 10(12): 2861-2892. DOI: 10.3390/md10122861.

Gennarino V.A., D'Angelo G., Dharmalingam G., Fernandez S., Russolillo G., Sanges R., Mutarelli M., Belcastro V., Ballabio A., Verde P., Sardiello M., Banfi S. (2012). Identification of microRNA-regulated gene networks by expression analysis of target genes. Genome research, 22(6): 1163-1172. DOI: 10.1101/gr.130435.111. 

Giacomelli S., Melillo D., Lambris J.D., Pinto M.R. (2012). Immune competence of the Ciona intestinalis pharynx: Complement system-mediated activity. Fish & Shellfish Immunology, 33: 946-952. DOI: 10.1016/j.fsi.2012.08.003.

Josef N., Amodio P., Fiorito G., Shashar N. (2012). Camouflaging in a complex environment-octopuses use specific features of their surroundings for background matching. PLoS ONE, 7(5): e37579. DOI: 10.1371/journal.pone.0037579.

Junca A., Gonzalez Marti B., Tosti E., Cohen M., De la Fontaine D., Benkhalifa M., Ménézo Y. (2012). Sperm nucleus decondensation, hyaluronic acid (HA) binding and oocyte activation capacity: different markers of sperm immaturity? Case reports. Journal of Assisted Reproduction and Genetics, 29(4): 353–355. DOI: 10.1007/s10815-012-9710-5.

López-Doménech G., Serrat R., Mirra S., D’Aniello S., Somorjai I., Abad A., Vitureira N., García-Arumí E., Alonso M.T., Rodriguez-Prados M., Burgaya F., Andreu A.L., García-Sancho J., Trullas R., García-Fernàndez J., Soriano E. (2012). The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interacts with Miro and Trak2. Nature Communications, 3: 814. DOI: 10.1038/ncomms1829.

Marrone V., Piscopo M., Romano G., Ianora A., Palumbo A., Costantini M. (2012). Defensome against toxic diatom aldehydes in the sea urchin Paracentrotus lividus. PLoS ONE, 7: e31750. DOI: 10.1371/journal.pone.0031750.

Mattiello T., Costantini M., Di Matteo B., Livigni S., Andouche A., Bonnaud L., Palumbo A. (2012). The dynamic nitric oxide pattern in developing cuttlefish Sepia officinalis. Developmental Dynamics, 241(2): 390-402. DOI: 10.1002/dvdy.23722. 

Oliveira P., Sanges R., Huntsman D., Stupka E., Oliveira C. (2012). Characterization of the intronic portion of cadherin superfamily members, common cancer orchestrators. European Journal of Human Genetics, 20(8): 878-883. DOI: 10.1038/ejhg.2012.11. 

Pascual-Anaya J., Adachi N., Alvarez S., Kuratani N., D’Aniello S., Garcia-Fernàndez J. (2012). Broken colinearity of amphioxus Hox cluster. EvoDevo, 3: 28. DOI: 10.1186/2041-9139-3-28.

Pinheiro H., Carvalho J., Oliveira P., Ferreira D., Pinto M.T., Osório H., Licastro D., Bordeira-Carriço R., Jordan P., Lazarevic D., Sanges R., Stupka E., Huntsman D., Seruca R., Oliveira C. (2012). Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis. Human molecular genetics, 21(19): 4253-4269. DOI: 10.1093/hmg/dds248.

Porreca I., De Felice E., Fagman H., Di Lauro R., Sordino P., (2012). Zebrafish bcl2l is a survival factor in thyroid development. Developmental Biology, 366(2): 142-152. DOI: 10.1016/j.ydbio.2012.04.013.

Santella L., Vasilev F., Chun J.T. (2012). Fertilization in echinoderms. Biochemical and biophysical research communications, 425(3): 588-594. DOI: 10.1016/j.bbrc.2012.07.159.

Silvestre F., Fissore R.A., Tosti E., Boni R. (2012). Ca²⁺ rise at in vitro maturation in bovine cumulus-oocyte complexes. Molecular reproduction and development, 79(6): 369-379. DOI: 10.1002/mrd.22038.

Thessalou M., Aydogan Ö., Bekas P., Bilge G., Boyaci Y.Ö., Brunelli E., Circosta V., Crocetta F., Durucan F., Erdem M., Ergolavou A., Filiz H., Fois F., Gouva E., Kapiris K., Katsanevakis S., Kljajić Z., Konstantinidis E., Κonstantinou G., Koutsogiannopoulos D., Lamon S., Mačić V., Mazzette R., Meloni D., Mureddu A., Paschos I., Perdikaris C., Piras F., Poursanidis D., Ramos-Esplá A.A., Rosso A., Sordino P., Sperone E., Sterioti A., Taşkin E., Toscano F., Tripepi S., Tsiakkiros S., Zenetos A, (2012). New Mediterranean Biodiversity Records. Mediterranean Marine Science, 13(2): 312-327. DOI: 10.12681/mms.313.

Vasilev F., Chun J.T., Gragnaniello G., Garante E., Santella L. (2012). Effects of Ionomycin on egg activation and early development in starfish. PLoS One, 7(6): e39231. DOI: 10.1371/journal.pone.0039231.

Other Publications

Dishaw L.J., Flores-Torres J.A., Mueller M.G., Karrer C.R., Skapura D.P., Zucchetti I., De Santis R., Pinto M.R., Litman G.W. (2012). A Basal chordate model for studies of gut microbial immune interactions. Frontiers in Immunology, 3: 96. DOI: 10.3389/fimmu.2012.00096.

2011

Brown ER, Piscopo S (2011). Ion channels in key marine invertebrates; their diversity and potential for applications in biotechnology. Biotech. Adv., 29: 457-467

Canali E, Ponte G, Belcari P, Rocha F, Fiorito G, 2011. Evaluating age in Octopus vulgaris: estimation, validation and seasonal differences. Marine Ecology Progress Series, 441: 141-149.

Crocetta F. (2011). Marine alien Mollusca in the Gulf of Trieste and neighbouring areas: a critical review and state of knowledge (updated in 2011). Acta Adriatica, 52: 247-260  

Crocetta F., Mifsud S., Paolini P., Piscopo J., Schembri P.J. (2011). New records of the genus Pachygrapsus (Crustacea: Decapoda) from the central Mediterranean Sea with a review of its Mediterranean zoogeography. Medit. Mar. Sci., 12: 75-93 

D'Aniello E., Pezzotti M.R., Locascio A., Branno M. (2011). Onecut is a direct neural-specific transcriptional activator of Rx in Ciona intestinalis. Developmental Biology, 355: 358-371

De Gregoris T.B.; Rupp O., Klages S., Knaust F., Bekel T., Kube M. Burgess J.G.; Arnone M.I., Goesmann A., Reinhardt R., Clare A.S. (2011). Deep sequencing of naupliar-, cyprid- and adult-specific normalised Expressed Sequence Tag (EST) libraries of the acorn barnacle Balanus amphitrite. Biofouling, 27: 367-374

Dishaw L.J.; Giacomelli S.; Melillo D.; Zucchetti I.; Haire R.N., Natale L., Russo N.A., De Santis R., Litman G.W., Pinto M.R. (2011). A role for variable region-containing chitin-binding proteins (VCBPs) in host gut-bacteria interactions. PNAS, 108: 16747-16752

Esposito C.L.. Passaro D., Longobardo I., Condorelli G., Marotta P., Affuso A., de Franciscis V., Cerchia L. (2011). A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death. PLOS ONE, 6: e24071  

Fagman H., Amendola E., Parrillo L., Zoppoli P., Marotta P., Scarfo M., De Luca P., de Carvalho D.P., Ceccarelli M., De Felice M., Di Lauro R. (2011) Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning. Dev. Biol., 359: 163-17

Fortunato A., Tosti E. (2011). The impact of in vitro fertilization on health of the children: an update. Eur. J. Obst. Gyn Repr. Biol, 154: 125-129

Fortunato A.E., Langellotto F., Sordino P. (2011). Identification and expression of soul/p22HBP genes in zebrafish, Gene Expression Patterns, 11: 360-369

Gallo A., Silvestre F., Cuomo A., Papoff F., Tosti E. (2011). The impact of metals on the reproductive mechanisms of the ascidian Ciona intestinalis. Mar Ecol.-Evol Perspect., 32: 222-231

Margheri L, Ponte G, Mazzolai B, Laschi C and Fiorito G, 2011. Non-invasive study of Octopus vulgaris arm morphology using ultrasound. Journal of Experimental Biology, 214: 3727-3731.

Natale A., Sims C., Chiusano M.L., Amoroso A., D'Aniello E., Fucci L., Krumlauf R., Branno M., Locascio A. (2011). Evolution of anterior Hox regulatory elements among chordates. BMC Evol. Biol., 11: 330  DOI: 10.1186/1471-2148-11-330 

Romano G., Costantini M., Buttino I., Ianora A., Palumbo A. (2011). Nitric Oxide Mediates the Stress Response Induced by Diatom Aldehydes in the Sea Urchin Paracentrotus lividus. PLOS ONE, 6: e25980

Santella L., Chun J.T. (2011). Actin, more than just a housekeeping protein at the scene of fertilization. SCIENCE CHINA-LIFE SCIENCES, 54: 733-743

Shomrat T, Graindorge N, Bellanger C, Fiorito G, Loewenstein Y, and Hochner B, 2011. Alternative Sites of Synaptic Plasticity in Two Homologous ‘"Fan-out Fan-in"’ Learning and Memory Networks. Current Biology, 21: 1-10. 

Silberschmidt, D., Rodriguez-Mallon, A., Mithboakar, P., Cali, G., Amendola, E., Sanges, R., Zannini, M., Scarfo, M., De Luca, P., Nitsch, L., Di Lauro, R., De Felice, M (2011). In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1. BMC Dev. Biol., 11:9  DOI: 10.1186/1471-213X-11-9

Silvestre, F., Gallo, A., Cuomo, A., Covino, T., Tosti, E (2011). Role of cyclic AMP in the maturation of Ciona intestinalis oocytes. Zygote, 19: 365-371

Squarzoni, P., Parveen, F., Zanetti, L., Ristoratore, F., Spagnuolo, A (2011). FGF/MAPK/Ets signaling renders pigment cell precursors competent to respond to Wnt signal by directly controlling Ci-Tcf transcription. Development, 138: 1421-1432

Tosti, E., Gallo, A., Silvestre, F (2011). Ion Currents Involved in Oocyte Maturation, Fertilization and Early Developmental Stages of the Ascidian Ciona intestinalis. Molec. Reprod. Develop., 78: 854-860 

Tricarico E, Borrelli L, Gherardi F, Fiorito G, 2011. I Know My Neighbour: Individual Recognition in Octopus vulgaris. Plos One, 6(4): e18710

Ullrich-Luter, EM., Dupont, S., Arboleda, E., Hausen, H., Arnone, MI (2011). Unique system of photoreceptors in sea urchin tube feet. PNAS, 108: 8367-8372

Zenetos, A., Katsanevakis, S., Poursanidis, D., Crocetta, F., Damalas, D., Apostolopoulos, G., Gravili, C., Vardala-Theodorou, E., Malaquias, M (2011). Marine alien species in Greek Seas: Additions and amendments by 2010. Medit Marine Sci., 12: 95-120

Chapters

Procaccini G., Affinito O., Toscano F., Sordino P. (2011) A New Animal Model for Merging Ecology and Evolution Evolutionary Biology In: Concepts, Biodiversity, Macroevolution and Genome Evolution, Pontarotti P. (Ed), Springer Berlin Heidelberg, p. 91-106

22 October-2 November 2018
Stazione Zoologica Anton Dohrn Naples, Italy

For many zooplanktonic species, the taxonomic status is still unresolved because the descriptions are insufficient for the complexity of morphological characters. Moreover, many cryptic or sibling species have been recently detected with molecular analyses. Only the integration of morphological and molecular approaches, coupled with phylogenetic analyses, will allow us to resolve the taxonomic problems that still hinder our clear comprehension of species distribution and evolution.

The Marine Organism Taxonomy Service at the Stazione Zoologica Anton Dohrn of Naples has launched a series of Advanced Zooplankton Courses (AZC) to provide an advanced training on integrative morphological and molecular taxonomy of marine zooplankton.

AZC1 will be focused on copepods and will improve and update the expertise in species identification of selected families: Aetideidae, Paracalanidae, Spinocalanidae, Corycaeidae, Oithonidae, and Oncaeidae, which are diverse, common and abundant in epipelagic and/or mesopelagic oceanic waters.

The course will also provide an opportunity to interact and discuss with specialized experts on new challenges of marine copepods taxonomy in the molecular era.

AZC1 is open to 20 participants with documented experience in copepod identification.

Registration fee: 600 €

EMBRC supports AZC1 with funds to cover the fee for three participants.

First Announcement

For more information

INBALANCE - INvertebrate-BActeriaL Associations as hotspots of benthic Nitrogen Cycling in Estuarine ecosystems

While traditionally, bacteria have been considered driving much of the Earth’s nitrogen (N) cycle, recent research shows that ecological interactions between meio-, macrofauna and bacteria are important in regulating N cycling in soft sediments. Thus, the INBALANCE Project aims to unveil the quantitative importance of ecological interactions between microorganisms and their benthic invertebrate hosts in regulating N cycling in shallow estuarine sediments. In particular, this project will investigate the identity and activity of bacteria associated with benthic invertebrate hosts, the most abundant functional group of meio- and macrofauna in estuarine systems, across the full range of possible interactions, from strict symbioses to casual associations.

Partners

Klaipeda University, Lithuania; Stockholm University, Sweden; Cawthron Institute, New Zealand; Università degli Studi di Parma, Italy; Stazione Zoologica Anton Dohrn, Italy.

Project Lifetime

2018 – 2021

SZN Role

Partner

SZN Principal Investigator

Ulisse Cardini

Project Coordinator

Mindaugas Zilius (Klaipeda University, Lithuania)

Funding Body

Research Council of Lithuania (LMT) under the European Social Funds (ESF) programme