Ph.D. Student
Marine Biotechnology Department
Stazione Zoologica Anton Dohrn
Villa Comunale
80121 Napoli - Italia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Skype: federicadicostanzo93
Director of Studies: Giovanna Romano
Internal Supervisor: Valeria Di Dato
Program: PhD in Biology XXXIV cycle, Università degli studi di Napoli Federico II
Research Interests
Microalgae are a group of eukaryotic and unicellular microorganisms with a great morphological and metabolic diversity. Among them, diatoms are of particular importance in the biogeochemical cycles of many nutrients and are responsible of the great part of the primary productivity of the oceans. The diatom Thalassiosira rotula, typical of the Gulf of Naples, is the chosen candidate of my PhD studies, since it showed in previous works the ability to produce bioactive molecules with biotechnological applications.
My PhD project is focused on drug discovery, a very promising field especially in relation to diatoms, as they produce a great variety of bioactive molecules for defence, communication and adaptation to different environments.
Publications
Di Costanzo F., Di Dato V., Ianora A., Romano G. Prostaglandins in marine organisms: a review. Mar. Drugs 2019, 17, 428;
Di Dato V., Di Costanzo F., Barbarinaldi R., Perna A., Ianora A., Romano G. Unveiling the presence of biosynthetic pathways for bioactive compounds in the Thalassiosira rotula transcriptome. Sci. Rep. 2019, 9:9893;
Di Dato V., Barbarinaldi R., Amato A., Di Costanzo F., Fontanarosa C., Perna A., Amoresano A., Esposito F., Cutignano A., Ianora A., Romano G. Variation in prostaglandin metabolism during growth of the diatom Thalassiosira rotula Sci. Rep. 2020, 10.5374.
