Technologist
Biology and Evolution of Marine Organisms Department
Tel. +39 081 5833333
Fax: +39 081 7641355
e-mail giovanna.benvenuto(at)szn.it
Skype: giobenv
Research interests
Cell biologist by training, my research interests focus on the molecular mechanisms controlling dynamic changes within a cell. Protein expression, modification, and localization in the cell and its architecture are subjected to continuous changes in response to both intrinsic properties of that cell and to external stimuli related to intercellular communication and/or interaction with the environment. The approaches used are: (i) protein expression/modification in vivo, (ii) light and confocal microscopy, (iii) electron microscopy.
Current projects include:
- Analysis of the formation and germination of resting stages (spores) in diatomes
- Development of experimental approaches for single-cell organism analysis
- Analysis of protein stability during embryogenesis
- In vivo imaging of mesenchymal to epithelial transition
Journal Papers
Zhou, C., Vitiello, V., Casals, E., Puntes, V.F., Iamunno, F., Pellegrini, D., Changwen, W., Benvenuto, G.*, Buttino, I.*. Toxicity of nickel in the marine calanoid copepod Acartia tonsa: Nickel chloride versus nanoparticles. 2016. Aquat Toxicol. 170:1-12. doi: 10.1016/j.aquatox.2015.11.003. *equal contribution
Vicidomini, R., Di Giovanni, A., Petrizzo, A., Iannucci, A., Benvenuto, G., Nagel, A., Preiss, A. and Furia, M. Loss of Drosophila pseudouridine synthase triggers apoptosis-induced proliferation and promotes cell-nonautonomous EMT. 2015. Cell Death Dis. 2015. Mar 26,6:e1705.
Santamaria, G., Esposito, CL., Cerchia, L., Benvenuto, G., Nanjappa, D., Sarno, D., Zingone, A., De Franciscis, V. and Ribera d’Alcalà, M. Aptamers are an innovative and promising tool for phytoplankton taxonomy and biodiversity research. 2015. Chemistry and Ecology.1-12.
Bosnjak, I., Borra, M., Iamunno, F., Benvenuto, G., Ujevic, I., Buselic, I., Roje-Busatto, R., Mladineo, I. Effect of bisphenol A on P-glycoprotein-mediated efflux and ultrastructure of the sea urchin embryo. 2014. Aquat. Toxicol. 156: 21-29.
Carotenuto, M., De Antonellis, P., Liguori, L., Benvenuto, G., Magliulo, D., Alonzi, A., Turino, C., Attanasio, C., Damiani, V., Bello, AM., Vitiello, F., Pasquinelli, R., Terracciano, L., Federico, A., Fusco, A., Freeman, J., Dale, TC., Decraene, C., Chiappetta, G., Piantedosi, F., Calabrese, C. and Zollo, M. H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC. 2014. Oncotarget 5(14):5736-49.
Escalera, L., Benvenuto, G., Scalco, E., Zingone, A. and Montresor, M. Ultrastructural features of the benthic dinoflagellate Ostreopsis cf. ovata (Dinophyceae). 2014. Protist. 165(3):260-74.
Castells, E., Molinier, J., Benvenuto, G., Bourbousse, C., Zabulon, G., Zalc, A., Cazzaniga, S., Genschik, P., Barneche, F. and Bowler, C. The conserved factor DE-ETIOLATED1 cooperates with CUL4-DDB1DDB2 to maintain genome integrity upon UV stress. 2011. EMBO J. 30(6):1162-72.
Dubin, M.J., Bowler, C. and Benvenuto, G. Overexpressing tagged proteins in plants using a modified Gateway cloning strategy. 2010. Cold Spring Harb Protoc. 2010(3):pdb.prot5401.
Dubin, M.J., Bowler, C. and Benvenuto, G. A modified Gateway cloning strategy for overexpressing tagged proteins in plants. 2008. Plant Methods 4:3.
Bernhardt, A., Lechner, E., Hano, P., Schade, V., Dieterle, M., Anders, M., Dubin, M.J., Benvenuto, G., Bowler, C., Genschik, P. and Hellmann, H. CUL4 associates with DDB1 and DET1 and its downregulation affects diverse aspects of development in Arabidopsis thaliana. 2006. Plant J. 47:591-603.
